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Dr. William Cance, MD
UACC Dignity Health
Get to Know Dr. Cance
Duke University School Of Medicine 1982
Barnes Jewish Hospital
Meml Sloan Kettering Cancer 1990
Barnes Jewish Hospital 1983
Dr. Cance's Experience
Awards & Recognitions
In My Own Words
Dr. Cance's research interests focus on focal adhesion kinase (FAK), a critical survival signal in cancer and a promising therapeutic target being evaluated in several clinical trials using kinase enzyme inhibitors. He was the first researcher to clone human FAK in 1993 and demonstrate its overexpression in almost all human cancers. Today, Dr. Cance is homing in on the biology of FAK and developing anti-cancer drugs that target the signal. He also is interested in the role of FAK in integrating cancer cell signaling that enhances the survival mechanisms of cancer cells. An avid researcher, Dr. Cance is the principal investigator on a current R01 grant from the National Cancer Institute (NCI) focusing on Focal Adhesion Kinase (FAK). He has been awarded numerous other grants from the NCI and National Institutes of Health, as well as the American Cancer Society, Susan G. Komen Breast Cancer Foundation and the U.S. Department of Defense. Dr. Cance received his medical degree from Duke University School of Medicine and was the chief resident in the Department of Surgery at Barnes Hospital Washington University School of Medicine in St. Louis, Mo. He also completed two fellowships, one in surgical oncology at Memorial Sloan-Kettering Cancer Center in New York and the other in the Departments of Surgery and Microbiology and Immunology at Washington University School of Medicine. Dr. Cance holds eight U.S. patents, including a patent for kinase protein binding inhibitors and one for devices and methods for implementing endoscopic surgical procedures and instruments within a virtual environment. He also has four patents pending. Dr. Cance is past president of the Society of Surgical Oncology, a member of the American Association of Endocrine Surgeons, American Association for Cancer Research, American Surgical Association, Society of Clinical Surgery and American Society of Clinical Oncology, as well as a Fellow of the American College of Surgeons. In addition, he served on the editorial board of the Annals of Surgical Oncology and the Journal of Clinical Oncology. He also served on the Board of Scientific Counselors of the National Cancer Institute. He is author of more than 130 peer-reviewed publications and 10 book chapters, and is founding editor-in-chief of the Society of Surgical Oncology-branded database of Complex General Surgical Oncology.
Dr. Cance's Locations
Accepting New Patients
UACC Dignity Health
625 N 6th St, Phoenix, AZ 85004
Dignity Health - St. Joseph's Hospital and Medical Center
350 W Thomas Rd, Phoenix, AZ 85013