Dignity Health Chandler Regional Medical Center in Arizona

Research Studies in Arizona

Dignity Health hospitals in Arizona have three pillars: patient care, medical education and research.

Our physicians and researchers are dedicated to investigating and discovering new and powerful therapies with one ultimate goal - to enhance patient care. With both basic research laboratories as well as hundreds of clinical trials, patients have access to state-of-the-art treatments.

Studies Open for Enrollment

    A Phase 2 Double-Blind Placebo-Controlled Single-Dose Study of Pharmacodynamics, Pharmacokinetics, Safety, and Tolerability of REGN7544, an NPR1 Antagonist Monoclonal Antibody, in Patients With Postural Orthostatic Tachycardia Syndrome

Principal Investigator: Rachel Bond, MD

https://clinicaltrials.gov/study/NCT06593600?term=NCT06593600&rank=1

For questions, please call 602-214-0886

A Phase 2/3 Efficacy and Safety Study of KPL-387 Treatment in Participants With Recurrent Pericarditis

Principal Investigator: Rachel Bond, MD

https://clinicaltrials.gov/study/NCT07010159?term=NCT07010159&rank=1

For questions, please call 602-214-0886

  • MAGICAL SV- MagicTouch™Sirolimus-Coated Balloon for Treatment of Coronary Artery Lesions in Small Vessels.

Principal Investigator: Nabil Dib, MD

https://clinicaltrials.gov/study/NCT06271590?term=NCT06271590&rank=1

For questions, please call 602-214-0886

  • SOS-AMI- Selatogrel Outcome Study in Suspected Acute Myocardial Infarction

Principal Investigator: Nabil Dib, MD

https://clinicaltrials.gov/study/NCT04957719?term=NCT04957719&rank=1

For questions, please call 602-214-0886

  • PICANTE - PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm

Principal Investigator: Ashish Pershad, MD

https://clinicaltrials.gov/study/NCT06445608?term=NCT06445608&rank=1

For questions, please call 602-214-0886

  • MAGICAL ISR- MagicTouch™ Sirolimus- Coated Balloon for Treatment of In-Stent Restenosis in Coronary Artery Lesions.

Principal Investigator: Nabil Dib, MD

https://clinicaltrials.gov/study/NCT06271590?term=NCT06271590&rank=1

For questions, please call 602-214-0886

  • LIBREXIA ACS- A Phase 3, Randomized, Double-blind, Placebo-controlled, Event-driven Study to Demonstrate the Efficacy and Safety of Milvexian, an Oral Factor XIa Inhibitor, After a Recent Acute Coronary Syndrome

Principal Investigator: Nabil Dib, MD

https://clinicaltrials.gov/study/NCT05754957?term=NCT05754957&rank=1

For questions, please call 602-214-0886

  • ARTEMIS- Effects of Ziltivekimab Versus Placebo on Cardiovascular Outcomes in Patients With Acute Myocardial Infarction

Principal Investigator: Nabil Dib, MD

https://clinicaltrials.gov/study/NCT06118281?term=NCT06118281&rank=1

For questions, please call 602-214-0886

  • ACCLAIM-Lp(a)- A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Investigate the Effect of Lepodisiran on the Reduction of Major Adverse Cardiovascular Events in Adults With Elevated Lipoprotein(a) Who Have Established Atherosclerotic Cardiovascular Disease or Are at Risk for a First Cardiovascular Event

Principal Investigator: Nabil Dib, MD

https://clinicaltrials.gov/study/NCT06292013?term=NCT06292013&rank=1

For questions, please call 602-214-0886

POLARx PAS - Prospective Multi-Site Safety and Effectiveness Study of the Boston Scientific Cardiac Cryoablation System for Drug Refractory, Recurrent Symptomatic Paroxysmal Atrial Fibrillation

Principal Investigator: Jaskanwal Bisla, MD

https://clinicaltrials.gov/study/NCT06170606?term=NCT06170606&rank=1

For questions, please call 602-214-0886

  • EMBLOK II - Evaluation of Safety and Effectiveness of the EMBLOK EPS Compared With No Cerebral Embolic Protection During TAVR

Principal Investigator: Ashish Pershad, MD

https://clinicaltrials.gov/study/NCT07129421?term=NCT07129421&rank=1

For questions, please call 602-214-0886

  • EMPOWER Trial - Assessment of the Carillon Mitral Contour System® in Treating Heart Failure With at Least Mild Functional Mitral Regurgitation

Principal Investigator: Nabil Dib, MD

https://clinicaltrials.gov/study/NCT03142152?term=NCT03142152&rank=1

For questions, please call 602-214-0886

  • ECMO LENS - A Multicentric Left Ventricular Venting Strategy Comparison in Patients Receiving Extracorporeal Life Support - A Prospective Observational Study.

Principal Investigator: Kristopher Roach, MD

For questions, please call 480-601-5411

  • Left vs Left - Cardiac Resynchronization Therapy Using His/Left Bundle Branch Pacing vs Biventricular Pacing With a Left Ventricular Epicardial Lead in Patients With Heart

Failure (HF) With Left Ventricular Ejection Fraction (LVEF)≤50% and With Either a Wide QRS Complex (>130 ms) or With/Anticipated >40% Pacing Randomized Clinical Trial

Principal Investigator: Jaskanwal Bisla, MD

https://clinicaltrials.gov/study/NCT05650658?term=NCT05650658&rank=1

For questions, please call 602-214-0886

SELUTION4BTK Trial - A Prospective Randomized Multicenter Single Blinded Study to Assess the Safety and Effectiveness of the SELUTION SLR™ 014 Drug Eluting Balloon in the Treatment of Below-the-Knee (BTK) Atherosclerotic Disease in Patients With Chronic Limb Threatening Ischemia (CLT

Principal Investigator: Dan Sraow, MD

https://clinicaltrials.gov/study/NCT05055297?term=NCT05055297&rank=1

For questions, please call 602-214-0886

  • IVY BRAIN TUMOR CENTER DATA AND TISSUE SCREENING PROTOCOL - A registry to collect blood or tumor samples of participants from previous or planned surgeries to determine if the tumors indicate a match to one of the available treatment clinical trial protocols.

Principal Investigator: Kaith Almefty, MD

For questions, please call 480-601-5411

  • BDTX - A Phase 0/1 Study of BDTX-1535 in Recurrent High-Grade Glioma (HGG) and Newly Diagnosed Glioblastoma (nGBM) Participants With EGFR Alterations or Fusions Scheduled for Resection to Evaluate Central Nervous System (CNS) Penetration With PK-triggered Expansion Cohort.

https://clinicaltrials.gov/study/NCT06072586?term=NCT06072586&rank=1

Principal Investigator: Kaith Almefty, MD

For questions, please call 480-601-5411

VBI-S-02 - A Phase III, Open Label, Randomized, Controlled Study of VBI-S in the Treatment of Hypovolemia in Patients With Septic Shock

Principal Investigator: Kristopher Roach, MD

https://clinicaltrials.gov/study/NCT06072430?term=NCT06072430&rank=1

For questions, please call 480-601-5411

KOURAGE - Auxora for the Treatment of AKI and Modulation of Injurious "Crosstalk" With the Lung: A Randomized Control Trial

Principal Investigator: Kristopher Roach, MD

https://clinicaltrials.gov/study/NCT06374797?term=NCT06374797&rank=1

For questions, please call 480-601-5411

ReInvigorate - Randomized Study of the pdSTIM™ System (Phrenic Nerve to Diaphragm STIMulation) in Failure to Wean Mechanically Ventilated Patients

Principal Investigator: Kristopher Roach, MD

https://clinicaltrials.gov/study/NCT05998018?term=NCT05998018&rank=1

For questions, please call 480-601-5411

  • HIP ATTACK-2 - HIP Fracture Accelerated Surgical TreaTment And Care tracK 2

Principal Investigator: William Naylor, MD

https://clinicaltrials.gov/study/NCT04743765?term=NCT04743765&rank=1

  • BvV - A Randomized Controlled Trial Comparing Antibiotic Cement Bead Pouch Versus Negative Pressure Wound Therapy for the Management of Severe Open Tibia Fracture Wounds

Principal Investigator: William Naylor, MD

https://clinicaltrials.gov/study/NCT05615844?term=NCT05615844&rank=1

For questions, please call 480-601-5411

  • ABBOTT i-STAT EG7+Cartridge - Clinical Evaluation of the Sodium, Potassium, Ionized Calcium, Hematocrit, pH, PO2, and PCO2 Tests in Non-Anticoagulated Venous and Arterial Whole Blood Specimens using the i-STAT EG7+ Cartridge with the i-STAT 1 Analyzer

Principal Investigator: Andrea Wolff, MD

  • Tbit™ system -A Prospective, Multi-Center, Non-Randomized Study to Identify Intracranial Hemorrhage by Using an In-Vitro Device, Tbit™ System

Principal Investigator: Brian Tiffany, MD

https://clinicaltrials.gov/study/NCT04107662?term=NCT04107662&rank=1

For questions, please call 480-601-5411

MOMENTUS- Multi-site Study of the Clinical Impact of an AI-assisted Approach to Referring Patients With Interstitial Lung Disease for Diagnostic Evaluation of Pulmonary Hypertension

Principal Investigator: Rajat Walia, MD

https://clinicaltrials.gov/study/NCT06911632?term=NCT06911632&rank=1

For questions, please call 480-601-5411

MAVERIX- Specimens for lung cancer panel design

Principal Investigator: Abid Khokar, MD

For questions, please call 480-601-5411